SAUL ROTHENBERG, PhD: Sleep is actually an elaborate, active physiological state. It's not a passive activity; your brain has mechanisms that drive you to sleep. At least one of the things that takes place during sleep is an active housecleaning by your immune system at the beginning of the night. And then the immune system has to be turned off at the end of the night to prevent the immune system from becoming too active.
ANNOUNCER: Without that rest, a host of problems can occur.
MICHAEL THORPY, MD: We're starting to learn about how it affects our metabolism, for example. We know it disrupts normal patterns of hormones and biochemical changes in the body. So sleep has an important role in regulating our body chemistry, keeping us alert during the day.
RAFAEL PELAYO, MD: The first thing that'll happen if you don't get enough sleep is that you'll have some problems with your memory. Usually word-finding difficulties, you can't get out the words exactly that you want to get. People get more irritable. People have trouble concentrating.
If somebody in the family does not sleep, it affects the entire family. When one person doesn't sleep well-and say it is the mother, for example-the children tiptoe around the house not to disturb the mother. She may feel bad, because she doesn't want to disturb the family. The family can maybe not make plans for the next day. They'll say, "Well, let's see how I sleep and then we decide." And the more they try to make the problem better, the worse it gets, the more frustration the family feels.
ANNOUNCER: Staying on top of the job can also be tough for people with sleep difficulties.